Preliminary Phytochemical Tests and Antioxidant Potential of Catharanthus Roseus Extracts
DOI:
https://doi.org/10.51983/ajeat-2015.4.2.760Keywords:
DPPH Assay, Phytochemicals, Antioxidant,, C.roseusAbstract
Periwinkle (nayantara) is the common name for a pair of perennial flowering shrubs belonging to the Apocynaceae family. The herb has been used for centuries to treat a variety of ailments and was a favourite ingredient of magical charms it was in the middle ages. The latin name for this herb is Catharanthusroseus, but it was classified as Vincarosea, and is still called by that name in some of the herbal literature. The present study explores the various phytochemicals present in the plant so as to substantiate its antioxidant property and also shows the several phytoconstituents that contribute to its various medicinal properties. Preliminary phytochemical screening of the crude extracts revealed the presence of alkaloids,flavanoids, tannins, saponins and phenolics. During DPPH assay of methanol extract of aerial part of Catharanthusroseusshows highest antioxidant activity of 92.04% in 200(μg/ml). The results confirm that aerial part of Catharanthusroseuscan be used as source of drugs to fight infections caused by susceptible bacteria.
References
S. K. Uniyal, K. N. Singh, P. Jamwal, and B. Lal, Traditional Use of Medicinal Plants, 2006.
P. K. Lai and J. Roy, "Antimicrobial and Chemopreventive Properties of Herbs and Spices," Curr. Med. Chem., pp. 451-1460, 2004.
S. Padua, J. K. Johnson, and M. Massiot, "Res.J. Med. & Med. Sci.," vol. 29, pp. 147, 1999.
C. Berrier, J. C. Jacquesy, M. P. Jouannetaud, and A. Renoux, "Hydroxylation and Bromination of Indolines and Tetrahydro-Quinolines in Superacids," New J. Chem., vol. 11, pp. 605, 1987.
C. J. Barnett, G. J. Cullinan, K. Gerzon, R. C. Hoying, W. E. Jones, W. M. Newlon, and G. A. Poore, "Structure-Activity Relationships of Dimeric Catharanthus Alkaloids. 1. Deacetylvinblastine Amide (Vindesine) Sulfate," J. Med. Chem., vol. 21, pp. 88, 1978.
J. T. Basker, R. P. Barris, and B. Carte, "Natural Products Drug Discovery: New Perspectives on International Collaboration," J. Net., vol. 58, pp. 1325-1357, 1995.
H. L. Pearce, "Medicinal Chemistry of Bisindole Alkaloids from Catharanthus," in The Alkaloids - Antitumor Bisindole Alkaloids from Catharanthus roseus (L.), A. Brossi and M. Su€ness, Eds. San Diego: Academic Press, pp. 145, 1990.
M. Ibrahim, S. M. Mehjabeen, and M. L. Narsu, "International of Pharmaceutical Applications," vol. 2, pp. 165-173, 2011.
S. Nayak, "Online Journal of Biological Sciences," vol. 6, no. 2, pp. 40-44, 2006.
S. T. Chang, J. H. Wu, S. Y. Wang, P. L. Kang, N. S. Yang, and L. F. Shyur, "Antioxidant Activity of Extracts from Acacia confusa Bark and Heartwood," J. Agric. Food Chem., vol. 49, pp. 3420-3424, 2001.
J. B. Harborne, Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis, 3rd ed. New York: Chapman and Hall, 1998, pp. 1-150.
A. M. El-Mahmood, J. H. Doughari, and F. J. Chanji, "In-Vitro Antibacterial Activities of Crude Extracts of Nauclealatifolia and Daniellaoliveri," Sci. Res. Essay, vol. 3, no. 3, pp. 102-105, 2008.
J. A. Duke and E. S. Ayensu, Medicinal Plants of China. Algonae, Mich.: Reference Publications 2, Medicinal Plants of the World, No. 4, 1985.
A. A. Nguyi, "Tannins of Some Nigerian Flora," Niger. J. Biotechnol., vol. 6, pp. 221-226, 1988.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2015 The Research Publication
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
